What is infectious mononucleosis ("mono")?

Infectious mononucleosis, "mono," "kissing disease," and glandular fever are all terms popularly used for the very common illness caused by the Epstein-Barr virus (EBV). This common viral infection causes fever, sore throat, and enlarged lymph nodes. The illness generally goes away without medical help. However, it may last from weeks to months. Treatment is mainly to ease symptoms, usually at home, with plenty of rest and fluids.